Summary: Parkinson’s disease (PD) is mainly characterized by striatal dopamine (DA) depletion due to loss of dopaminergic neurons in the Substantia Nigra pars compacta (SNpc). Progressive cell loss and greater nigro-striatal denervation are associated with increased motor deficits and suboptimal therapeutic control. Understanding the mechanisms that underlie the onset and progression of SNpc damage is […]
Author: asso.nba@gmail.com
Postdoctoral training opportunity in the Harraz Lab: Ion channel physiology/pathophysiology, Signal transduction & neurovascular coupling in Vermont University, Burlington (USA)
Summary: The successful candidate will investigate ion channels and receptors in the vascular system under physiological and pathophysiological conditions. The research will involve patch clamp electrophysiology, genetically engineered mouse models, primary cell culture, calcium imaging, and in vivo imaging of blood flow. We are specifically interested in individuals with research experience in vascular biology, ion […]
Postdoctoral position to develop engineered nanobodies targeting brain alpha7 nicotinic acetylcholine receptors. 2 years, Institut Paster, Paris
Summary: The alpha7 nAChRs are abundantly expressed in the brain in regions underlying cognition, especially in the hippocampus and the frontal cortex. There is strong evidence that their activation can ameliorate neurocognitive deficits in patients, notably in schizophrenic patients. In this context, we recently generated two single-chain antibodies from alpacas (nanobodies) targeting this receptor, one […]
Poste de Technicien-ne en expérimentation animale, histologie, immunohistochimie, IMN Centre Broca-Nouvelle aquitaine, Bordeaux (France)
Temps plein : 100% Durée du Contrat : 24 mois Missions Nous recherchons un-e technicien-ne biologiste pour participer à différents projets de recherche de l’équipe Monoamines, douleur et Parkinson à l’IMN. L’équipe s’intéresse à l’implication des systèmes monoaminergiques dans la physiopathologie et la thérapie de la douleur dans la maladie de Parkinson. La personne recrutée mettra […]
Junior Group Leader position. At the interdisciplinary institute of neuroscience NeuroStra, Strasbourg (France)
NeuroStra aims to recruit an outstanding junior scientist to develop a project in line with one of the following two priority axes: NeuroPain or NeuroDegen. The levels of investigation of the project can range from molecular to integrated ones, including clinical approaches in humans. Applicants should be dynamic early-career neuroscientists, with the potential to develop […]
1 Year Postdoctoral position: Chronic stress and synaptic changes linked to behavioural output, Coimbra (Portugal)
Subjet: Understanding how chronic stress leads to synaptic and cognitive/behavioural changes that may underlie neuropsychiatric disorders. An hypothesis would be that miRNA-186-5p could be a mediator of such changes. To whom: PhD in Biological Sciences or related with the following experiences: small surgeries in mice, stereotaxic injections, eletrophysiology, behavioral testing & animal experimentation certificate. This […]
Postdoctoral position Baltimore (USA): extracellular vesicles and neurodegeneration
The National Institute on Aging (NIA), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (DHHS), is recruiting for a Postdoctoral Fellow position in the Human Neuroscience Section (HNS) of the Laboratory of Clinical Investigation (LCI) in Baltimore, MD. Requirement: The candidates should have a […]
Offre de thèse à Paris (France)
Résumé du projet Les lésions médullaires cervicales conduisent à une des conditions les plus dévastatrices pour un individu. La perte d’intégrité de la moelle épinière corrompt les voies supra spinales descendantes et réduit les afférences, conduisant à une déficience motrice mais également à une atteinte respiratoire marquée. La majorité des patients tétraplégiques ont recours à la ventilation […]
Post-doctoral position in Neurosciences (1,5 years)
The research Unit T3S/Inserm U1124, constituted of 8 teams, has a general focus on Environmental Toxicity, Therapeutic Targets, Cellular Signaling and Biomarkers. Post-doctoral achievement will take place in Team 3 « Myelination and Nervous system pathologies ». The aim of the project focuses on the identification of at-risk subjects to develop depressive disorders and co-morbidities and the underlying mechanisms. The […]
Joint Ph.D. position from the University of Poitiers (France) and the University of Turku (Finland) – Cancer cell biology
The4CS Unit (CNRS ERL7003/University of Poitiers – France)and theCell migration lab (Turku Bioscience Centre, University of Turku – Finland) are looking for a joint Ph.D. student to study the role of mechanosensitive calcium channels during melanoma cancer progression. The position is partly funded by the European Campus of City-Universities (EC2U) project. The 4CS Unit focuses on identifying new […]