Duties and Responsibilities
The project involves applying electrophysiological techniques both in vivo (EMG recordings) and in vitro (slice and en bloc spinal cord) to understand how the circuitry for recurrent excitation and inhibition between motoneurones and Renshaw cells are affected at various
stages of ALS in two animal models.
The job holder will make use of state of the art facilities for probing circuit connectivity, including paired recordings between motoneurones and Renshaw cells (Bhumbra et al, JNeurosci. 2014, 34, 12919, Moore et al, J. Neurosci. 2015, 35, 13673) and two-photon holographic mapping of connectivity.
The successful candidate will have a PhD (awarded or submitted) in a relevant subject area and have a proven knowledge of the principle of electrophysiological recordings. This position will suit someone who has a keen interest in in spinal cord physiology, in health and
disease. Demonstrable comprehensive knowledge in the area of spinal cord physiology and proven proficiency in in vitro patch-clamp/intracellular recordings in the CNS is essential. Proven proficiency in both vitro electrophysiological recordings in the spinal cord and in vivo recordings of muscle activity is advantageous.
The post holder will have experience of successfully working in a competitive academic research environment and evidence of a good quality publication record. Please note: Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £30,316 – £31,967 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis (including corrections).
Full details on the role and the person specification can be accessed at the bottom of this page. Please ensure you read these carefully before applying for the post, as candidates must meet all essential criteria to be considered.
Link to UCL ad:
If you would like to discuss the post please contact:
Dr Marco Beato
Prof. Rob Brownstone
For any queries regarding the application process, please contact
Biosciences Staffing on firstname.lastname@example.org and quote the reference 1708682.