Deadline for application 31/07/23
Starting date: September 2023
Background
Neuro-Dol is an academic research facility affiliated with the French National Institute of Health and Medical Research (INSERM) and the University Clermont Auvergne (UCA). Situated within the CHU Estaing Hospital, our laboratory offers a spacious working area of approximately 750 m2, equipped to the highest standards with multidisciplinary resources.
Our team is dedicated to studying the cellular and molecular mechanisms of spinal and trigeminal pain with the aim of developing innovative treatment strategies. We adopt a comprehensive approach, conducting both preclinical and clinical investigations to gain insights into the neurobiological basis of pain and its effective management. Notably, our team has been honoured with the ANR Young Researcher award, and we actively participate in a dynamic and interdisciplinary research strategy. Moreover, we regularly organise pain seminars, national and international symposia, and various engaging activities for our team members.
Position information
Cutting-edge electrophysiology combined to living cell imaging, trans-synaptic tracing and behavioural analysis in genetically modified mice will be used so as to reveal and identify neuronal circuits within the spinal cord dorsal horn underlying chronic pain.
A 1-2-year(s) postdoctoral or research engineer position, fully funded by the French National Agency for Research (ANR), is available starting September 2023 at the Neuro-Dol Laboratory (Clermont-Ferrand, France).
In addition to being part of the Neuro-Dol task force, the successful candidate will interact with the scientific community, locally and at both national and international congresses.
Profile
Applicants must hold a PhD in Neuroscience and have a genuine interest in experimental biology.
The candidate should be comfortable with surgical procedures in rodents. Moreover, the successful candidate should be independent, well organised, rigorous and highly motivated.
Experience confocal or multi-photon imaging is a plus.
How to apply?
Candidates should send a resume, short statement of research interests (max 1 page) and at least 2 letters of reference to cedric.peirs@inserm.fr.
Useful links
For more information about the job position:https://neurodol.uca.fr/version-francaise/navigation/recrutement/postdoctoral-ir-position
Neuro-Dol lab: https://neurodol.uca.fr/
Dr Cédric Peirs’ researchgate: https://www.researchgate.net/profile/Cedric-Peirs
Five main publications related to the project:
- Peirs C, Williams SG, Zhao X, Arokiaraj CM, Ferreira DW, Noh MC, Smith KM, Halder P, Corrigan KA, Gedeon JY, Lee SJ, Gatto G, Chi D, Ross SE, Goulding M, Seal RP: Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury. Neuron, 2021 Jan 6;109(1):73-90.e7. (IF = 14.4)
- Peirs C and Seal RP: Neural circuits for pain: Recent advances and current views. Science, 2016 Nov 4;354(6312):578-584. Invited Review, (IF = 37.2)
- Peirs C, Bourgeois N, Artola A, Dallel R: PKCγ Interneurons Mediate C-Fiber-Induced Orofacial Secondary Static Mechanical Allodynia, but not C-Fiber-Induced Nociceptive Behavior. Anesthesiology, 2016 May
19;124(5):1136-52. (IF = 5.8) - Peirs C and Seal RP: Targeting Toll-like receptors to treat chronic pain. Nature Medicine, 2015 Nov 5;21(11):1251-2. Invited Comment, (IF = 30.4)
- Peirs C, Williams SP, Zhao X, Walsh CE, Gedeon JY, Cagle NE, Goldring AC, Hioki H, Liu Z, Marell PS, Seal RP: Dorsal Horn Circuits for Persistent Mechanical Pain. Neuron, 2015 Aug 19;87(4):797-812. (IF = 14.0)