Position proposal for a Doctor (M/F) in Neuroscience to pilot preclinical studies of an implantable medical device active in the field of neurodegenerative diseases.
RD2 Conseil is a recruitment firm specialized in the search for scientific profiles, in particular of «young doctors», for the R&D needs of SMEs and innovative startups, wishing to develop advanced skills and real human resources in innovation.
Our client is a Medtech startup created in 2021 and based in Grenoble.
Following 5 years of research and collaboration with academic partners, the company aims to develop an implantable medical device for neuroprotective therapy that targets including Parkinson’s disease (15 million people affected worldwide by 2030).
Although the symptoms can be treated, no therapy allows to slow down the associated neuronal degeneration. The aim of the device is to curb this degeneration to slow the progression of the disease and prevent worsening symptoms. It will offer future patients an ultra-innovative therapy based on the use of molecular hydrogen, recognized as a powerful and selective antioxidant.
This technology has many advantages: the treatment is chronic, minimally invasive and will significantly reduce the cost of the patient. A first version of the device was developed and a successful preclinical study on a parkinsonian rat model was performed. Next steps are to validate the tests preclinical to move to clinical trials.
The company’s ambition is to start testing in humans by the end of 2026. The technology has already been patented, three others are in progress. The startup now has great recognition thanks to the numerous Innovation Awards and is notably i-Lab 2023 Laureate.
Composed to date of three full-time employees, and supported by different partners (in particular 2 academic researchers invested in the project), the company plans to realize a new fundraising to support its growth. With this dynamic in mind, it wishes to today strengthen its team by recruiting an R&D Doctor (M/F) in Neurosciences. The recruited person will play a key role of teammate in the development of the device and more widely, in the development of the company. It will be under the direct responsibility of the founder and CEO of the company, she will work closely with the other people of the team and with the company’s partners (including academic laboratories).
The main challenge of the position is to steer the «therapy» axis of the project through the supervision of preclinical studies. The recruited person will be responsible for planning, coordinating and monitoring the preclinical roadmap: development, animal experiments, characterization, reports experimental. More specifically, you will be asked to:
- Identify risks and address them in a timely manner,
- Define the decision-making, reporting and monitoring process for project progress (closely collaboration with the CEO),
- Ensure compliance with regulatory guidelines in preclinical studies,
- Manage the project through its various dimensions: resources, deadlines, budget and follow-up of the steps (while making sure to integrate the changes related to the processed data),
- Conduct experiments on animal models (30-40% of your activity will be devoted manipulation),
- Ensure quality, clarity and completeness of project documentation, including regulatory records,
- Drive and monitor project communication planning.
- Ultimately, manage the relationship with the CROs, taking into account the business functions (legal, purchasing, finance).
Occasional telework is possible depending on the activity.
- PhD (M/F) in Neuroscience, specializing in neurodegenerative diseases (ideally on Parkinson’s disease),
- If possible with postdoctoral experience (in an industry biotechnological/pharmaceutical or in academic laboratories),
- Skills in animal experimentation, pharmacology, cell culture, electrophysiology,
- Knowledge of regulatory guidelines for preclinical studies preferred,
- Knowledge of a project management tool appreciated,
- Proficiency in English and French is required (oral/written).
- Good communicator with excellent interpersonal skills to interact with a plurality of interlocutors,
- Comfortable working collaboratively,
- Objective and results oriented, with a rendering requirement,
- Excellent organizational skills with the ability to manage multiple tasks and prioritize work,
- Analytical and synthetic mind to have a clear overview,
- Able to lead, negotiate and solve problems,
- Agile and able to adapt to changes inherent to the nature of the project and the the company (startup).
How to apply?
If you think you are this person, that you have a PhD and have never been hired on a permanent contract after your thesis (mandatory requirement to meet the CIR criteria), we invite you to send us your CV and cover letter by email to email@example.com – under reference THE.